With regards to the FTDX101D/MP, a few things were tweaked in the 220.127.116.113 version of Ham Radio Deluxe.
IMPORTANT: Given the confusion regarding the previous rig being labeled "FTDX101MP", we changed the name to reflect that BOTH rigs have the exact same commands with one exception (more about that in a moment).
The radio is now listed as the "FTDX-101D/MP" under the Yaesu list of radios. But after installing the update from 18.104.22.1681 to 22.214.171.1243, the radio that you had previously added will show up as "-unknown- FTDX-101MP" (as the demo version below):
Everything is fine. All you need to do is click on it, click "Remove" to remove the radio.
Then add the radio that appears as the "FTDX-101D/MP".
The only difference in these two radios is that the power on the "MP" goes to 200 watts and the "D" version goes to 100 watts. It's the same command. But if you have the "D" version and you drag the RF power slider above 100 watts, it will simply return back to the midpoint of the slider because it isn't capable of going above 100 watts. This is normal.